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Uses:

• Quinine is a drug that is primarily used for the treatment of malaria and is found naturally in the bark of the cinchona tree. Its exact method of action is not well understood, but it seems to accumulate in the red blood cells that have been infected with malaria and as a result destroys the parasites. It cannot cure malaria, as it has no effect on the parasitic form that exists outside of the red blood cell.
• Quinine is a medication used to prevent and treat malaria and to treat babesiosis. This includes to treat malaria due to Plasmodium falciparum that is resistant tochloroquine when is not available.While used for restless legs syndrome it is not recommended for this purpose.

• It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis.
• It may also be used as a phosphor for the detection of vacuum ultraviolet radiation and electrons.

• Sodium Salicylate is a gastric irritant and sodium bicarbonate is often given with it to reduce this effect (however the bicarbonate also increases rate of excretion and this lowers the concentration of salicylate in the blood).
• Some persons, especially asthmatics, exhibit notable sensitive which may provoke various reactions including urticaria, angioneurotic oedema, rhinitis and severe, even fatal, paroxysmal bronchospasm and dyspnoea.
• The haemorrhagic effects on gastric mucosa may be enhanced by anticoagulants.
• The activity of methotrexate may be markedly enhanced and its toxicity, increased and other may mask the respiratory symptoms of overdosage and have been reported to enhance its toxicity.

Paracetamol, also known as acetaminophen or APAP, is a medication used to treat pain and fever. It is typically used for mild to moderate pain. Evidence of benefit in a fever for children is poor. It is often sold in combination with other ingredients such as in many cold medications. In combination with pain medication, paracetamol is used for more severe pain such as cancer pain and after surgery. It is typically used either by mouth or rectally but is also available intravenously. Effects last between two and four hours. Paracetamol is generally safe at recommended doses. Serious skin rashes may rarely occur. Too high a dose can result in liver failure. It appears to be safe during pregnancy and when breastfeeding. In those with liver disease, it may still be used but lower doses should be taken. Paracetamol is classified as a mild analgesic. It does not have significant anti-inflammatory activity and how it works is not entirely clear.